Urine for Organic Acids (NBS) is the baby’s first test that
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chevron_rightUrine Organic Acid test is done postnatally, in early as well as later years of life.
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chevron_rightOrganic acid disorders are a group of rare conditions that affect metabolism. These are a group of disorders in which one or more of these pathways are blocked, resulting in a deficiency of normal products and an abnormal accumulation of intermediate metabolites(organic acids) in the body.
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chevron_rightNBS test is done on babys blood and urine samples to test for 50 different genetic conditions.
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chevron_rightChildren with these conditions cannot break down protein properly in the body and it causes harmful substances to build up in blood and urine.These excess metabolites are excreted in the urine.
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chevron_rightOrganic acidurias typically present with either an acute life-threatening illness in early infancy or unexplained developmental delay with intercurrent episodes of metabolic decompensations in later childhood.
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chevron_rightA situation of a severe and persistent metabolic acidosis of unexplained origin, elevated anion gap, and severe neurologic manifestations, such as seizures, should be considered strong diagnostic indicators of one of these diseases.
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chevron_rightHyperammonemia, hypoglycemia, and lactic acidemia are frequent findings, especially during acute episodes of metabolic decompensations.